NorTwinCan

Lung Cancer

Lung Cancer

The lifetime risk for lung cancer in a monozygotic twin is 3.6-fold (SE=0.6) times higher if the co-twin has lung cancer. For dizygotic pairs the relative risk is 2.4-fold (SE=0.3). This data indicates familial and further genetic influences to lung cancer. The relative genetic contribution does not decline with increasing age. The heritability of lung cancer did not change when smoking status was taken into account. However, the heritability varied by smoking status, and a manuscript is being finalized.